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Antiflame | SimplyBest
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Antiflame | SimplyBest

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Avg. Rating  star ratingstar ratingstar ratingstar rating  4 out of 5  - 18 product reviews
In StockIn Stock
E705: 120 Capsules £14.89
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SimplyBest Antiflame


  • For fast and effective pain relief
  • Made in the UK and GMP approved


What is SimplyBest Antiflame™?


This innovative formula contains Mangoselect®, which is extracted from the mangosteen fruit and concentrated to provide an impressive 10% of alpha-mangostin. Antiflame™ is extremely popular with customers looking for fast and effective pain relief.


Proven to support joint function


Clinical findings support the use of Mangoselect® as an effective pain reliever. A recent clinical trial for Mangoselect® split participants into two separate sub-groups: 

    • The first group included active sports men and women between the ages of 23 and 45. Their pain levels were monitored over a 5 day period. Findings showed that Mangoselect® reduced pain in joints by 31% after 5 days.

    • The second study included senior adults between the ages of 65 and 72 who suffered from arthritic joint pain. Findings showed that after 5 days, pain levels reduced by an average of 50%.

    Researchers concluded that Mangoselect® supports the body’s natural healing processes by reducing the levels of inflammatory markers that damage cartilage.


    A premium quality product


    As part of our SimplyBest™ range of premium quality supplements, Antiflame™ boasts unprecedented levels of purity and is manufactured to strict standards of quality. For optimum joint benefits, this is often taken in combination with Glucosamine Sulphate. 


     Nutritional InformationPer capsule
    % EC RDA
     RDA = Recommended Daily Allowance, µg = Microgramme
     mg = Milligram, IU = International Units

    Other ingredients: HPMC vegetarian capsule (titanium dioxide), Magnesium Stearate.

    V: Suitable for vegetarians
    Free from artificial additives and preservatives
    Lactose free
    Wheat free
    Fish free
    Gluten free
    Yeast free



    Take two capsules daily as a food supplement or as directed by a healthcare professional.



    If you are taking any prescription medication, you have a medical condition or you have specific concerns about the suitability of our products, always consult your GP or Pharmacist prior to taking supplements. Do not exceed stated dose. Store in a cool dry place. Keep away from children at all times. Do not use if seal is broken. Pregnant or lactating women should consult a Doctor before using this product. Image is for illustration purposes only. Food supplement: This product should not be used as a substitute for a varied diet. Suitable for Vegetarians.

    UK Mainland

    STANDARD: FREE 2-day tracked delivery for all online orders.

    All orders dispatched to UK addresses will automatically qualify for FREE Standard 2 Day Delivery, regardless of order size. This means you won't be waiting long for your goods to arrive. Order before 12.30pm Monday-Friday to receive goods within 2 working days. (excluding bank holidays) 

    EXPRESS: FREE next-day delivery for orders over £70.

    Place your order before 12.30pm Monday-Friday to receive your goods the next-working day (excluding bank holidays). For orders under £70 there is a small £5.25 charge for Express Next Day Delivery.

    Track your order

    All orders dispatched to UK addresses can be tracked. Simply follow the link in your dispatch confirmation email to locate your parcel. If you encounter any problems please call our freephone number 0800 988 0292 to speak to a customer service advisor.


    Europe & Rest of the World

    For all European and International orders, delivery charges will vary depending on the total weight and size of the order. As you add products to your basket the delivery charge will automatically update. This service offers all our international customers fair and competitive delivery charges.


    Terms & Conditions

    Orders must be placed before 12.30pm Monday to Friday (excluding bank holidays) to qualify for our Express Next Day Delivery or Standard 2 Day Delivery. These services are currently available for UK addresses only and are subject to stock levels. If an item(s) is out of stock, it will be given priority delivery upon arrival. For full terms and conditions please click HERE.

    Please Note: The views expressed below are those of Simply Supplements customers. Simply Supplements does not endorse these views, nor should they be regarded as medical advice.

    • 5 stars5 stars5 stars5 stars5 stars

      Reviewed on
      5th Feb 2014
      Fewer medications 
      Shannon, Lichfield
      I have lupus and used to suffer from severe fatigue and joint pain every single day. I have been taking these every morning for the past four months and have now managed to stop all but one of my medications, with my doctors approval. This is one of the strongest mangosteen tablets I've found and I've always been impressed with the quality of your supplements.  

    • 4 stars4 stars4 stars4 stars

      Reviewed on
      17th Oct 2013
      Hip pain  
      David, Stamford
      My dad has suffered from pain and immobility for years and recently had hip replacement surgery. I found Antiflame about six months before his surgery and he has used it ever since. Dad says it works wonders to reduce the pain he used to experience when moving around. Ive also just placed my first order for myself as my joints certainly aren't what they used to be.

    • 3 stars3 stars3 stars

      Reviewed on
      4th Jun 2013
      Great Product, Delivery not so much ... 
      Bryn Fountain, Wrexham
      This is a useful product but need it to be delivered on time so I can use it. I had to wait a couple days extra for the parcel to arrive but by that time I had run out. Will still continue using you as the products are flawless.

    • 5 stars5 stars5 stars5 stars5 stars

      Reviewed on
      8th Apr 2013
      Seafront Worker 
      Marcus Parker, Skegness
      As I work on the beach itself I am constantly on my feet all the time and before at the end of everyday from my knees down were constantly in pain and aching. Since i've discovered your company I thought I would give these a go and now after only a few months of taking them the aches and pains have greatly reduced. Very good Supplement.

    • 4 stars4 stars4 stars4 stars

      Reviewed on
      31st Jan 2013
      Worth Every Penny 
      Sylvia Parker, Rhyl
      This product has helped to reduce the inflammation around my knee very quickly and the pain has greatly reduced. Fantastic product and worth every penny.

    • 5 stars5 stars5 stars5 stars5 stars

      Reviewed on
      21st Dec 2012
      Much Better than Devils Claw 
      Suzie-anne Patterson, London
      I used to have Devils Claw from you for many years but sadley the EU decided we couldnt get it from you anymore so my attentions turned to the Antiflame. This has been more helpful than the Devils Claw. Even though it was very good this Antiflame seems to have done the job and given me more mobility aswell. Excellent product and highly recommended.

    • 5 stars5 stars5 stars5 stars5 stars

      Reviewed on
      19th Dec 2012
      Joint Pain 
      Karen Bostock, Axminster
      I used to take devils claw and was recommended this, its fantastic and really helps with my joint pains especially Knee & Back, i have also recommened to other friends and family who are just as pleased.

    • 4 stars4 stars4 stars4 stars

      Reviewed on
      31st Oct 2012
      cervical spondylosis 
      Suzanne Moore, Leominster
      I have suffered for over 30 years with this painful condition. Antiflame is really making a mark able difference to the level of pain in my joints. I was really skeptical but really needed some relief other than pain killers. Thank you simply supplements.

    • 5 stars5 stars5 stars5 stars5 stars

      Reviewed on
      4th Sep 2012
      A Long Time Working 
      Mr Denton, Dudley
      Bought these in February and only just feeling the benefits now. They have taken a good while to work but they have been helping.

    • 5 stars5 stars5 stars5 stars5 stars

      Reviewed on
      28th Aug 2012
      Joint pain  
      Mark Smith, Mirfield
      I have been suffering with various pains in my joint and decied to call and speak to one of your adviors who helped me decide on this product i have been using it for a about 10 weeks and its really helped my joints, it did take a little while before it started working but i am very happy with the results

    • 5 stars5 stars5 stars5 stars5 stars

      Reviewed on
      4th Jul 2012
      bad knees 
      Peter, chester
      i have been suffering with bad knees since i was younger and have been adv by a friend to try this product. I used to take devils claw but now use this instead. It really has helped ease the pain.

    • 5 stars5 stars5 stars5 stars5 stars

      Reviewed on
      17th Apr 2012
      Very helpful 
      Angela Downing, Evesham
      Prices are good compared with other companies and easy to order online. This product has been very helpful since changing from rosehip. My last order was delivered very quickly.

    • 5 stars5 stars5 stars5 stars5 stars

      Reviewed on
      2nd Apr 2012
      Replacement for Devils Claw! 
      John Knowles, Oxford
      I've been a customer for a long time and used to have Devils Claw on the autodespatch scheme. Since it has been discountinued they offered me Antiflame which is the best anti-inflammatory for my joints and I still have 10% off on repeat orders.

    • 5 stars5 stars5 stars5 stars5 stars

      Reviewed on
      7th Feb 2012
      Bigger would be better 

    • 4 stars4 stars4 stars4 stars

      Reviewed on
      6th Feb 2012
      Additional Support 
      Michael Lewis, Barton
      I have been using Glucosamine for some time and decided it was time for some additional support. I was advised to take Antiflame to help reduce the pain in my knee joints and am surprised by the results. I must point out it wasnt a quick fix, I had been taking the Glucosamine and Antiflame for a couple of months before I really noticed the effects. I have been taking this for 4 months now and wouldnt be without them. My knees feel loads better and I can do much more now before feeling any pain.

    • 5 stars5 stars5 stars5 stars5 stars

      Reviewed on
      16th Dec 2011
      Excellent customer service! 
      walter rice, worcester
      I recieved a simply supplements brochure a couple of weeks ago and decided i would like to place an order for a product that would help ease my aching joints, i already take glucosamine so i wanted to try something that would work along side it, i called the freephone orderline and spoke to an advisor who was really helpful and reccommended this product to me! ordering was quick and simple and i recieved my items within a few days!

    • 5 stars5 stars5 stars5 stars5 stars

      Reviewed on
      16th Dec 2011
      Fantastic product! 
      joan west, newark
      I started using this product in replacement of devils claw and it has been fantastic! I suffer from really bad pain in my joints and this has really helped to ease the pain and I am now more flexible too! 

    • 5 stars5 stars5 stars5 stars5 stars

      Reviewed on
      17th Aug 2011
      A BIG thank you!! 
      Margaret Smith, Harrogate
       I have been using Antiflame with Glucosamine and the pain in my joints has now eased a great deal and life is now a lot more enjoyable, thank you

    See all reviews

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    Review this product
    • 29th September 2014 - Robin
      Q: Does AntiFlame cause or contribute to high blood pressure?
      Should it be taken with blood pressure medication?
      A: Our Antiflame should not contribute to high blood pressure, however, everyone is different and therefore can react to supplements in different ways. Unfortunately, as we are not medically trained, we are unable to say whether these can be taken with bloody pressure tablets. We kindly suggest that you seek advice from your local pharmacist or GP prior to taking any supplements.
    • 17th November 2013 - Jack Grafton

      I have a reoccurring knee injury that is stopping me from weight training. Would Antiflame be the best option for me?


      Antiflame contains a mangosteen extract that has been shown to help reduce inflammation caused by joint injuries. Therefore, we would certainly recommend this product to you.

      You may also find it beneficial to take a Glucosamine supplement alongside Antiflame for optimum joint health.

    • 24th February 2013 - Sheila
      Q: Is this product suitable for arthritic pain in the fingers, also is it suitable for someone with tablet controlled diabetes to take?

      We would certainly recommend Antiflame to you, as studies have found that it may help to relieve inflammatory reactions in the joints. However, at Simply Supplements we are not medically trained, so we would advise you to consult with your GP with regards to taking Antiflame alongside prescription medication for diabetes.

    • 9th February 2013 - Hilary
      Q: Does antiflame contain any ibuprofen or substance that would cause adverse affects to a warfarin taker? My husband has arthritis & there are very few products that he can take for pain relief because he has to take warfarin for the rest of his life.

       This product does not contain any ibuprofen or similar ingredient. However, as we are not medically trained, we would suggest that he consults his GP before taking any supplements.

    • 28th August 2012 - Mrs Jones
      Q: Is the Anti-flame a direct replacemnent for Devils Claw?

      Yes, this product is a replacement for the discontinued Devils Claw.

    • 4th August 2012 - Eileen Wimshurst
      Q: Should Antiflame be taken with or instead of Glucosamine? My husband has been taking glucosamine for his arthritic knees for some time but needs something stronger.

      As supplements are not prescription medication, they will work in different ways for different people. If he would like to take both products alongside each other, providing he does not exceed the RDA of either product there should be no harm in doing this.


    • 28th June 2012 - bernadette monk
      Q: I have a frozen shoulder and just started taking devils claw. Is there anything stronger I can use as it is very painful, especially at night.

      AntiFlame has been specifically designed to support the body's healing processes, and has been shown to aid with joint pains. Therefore this is certainly something that we would recommend for you. As long as you do not exceed the recommended dosages for each product, then there should be no issue taking AntiFlame and Devil's Claw together.

    • 29th May 2012 - Nidhi
      Q: How many should you take per day?

       The recommended dosage for Antiflame is one capsule per day.

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